Table 3 Proteins measured in plasma of patients enrolled in CALGB 80303 and 80203.

From: Genetic variation determines VEGF-A plasma levels in cancer patients

Soluble Angiogenic Factors

Matrix-Derived Angiogenic Factors

Markers of Vascular Activation and Inflammation

ANG-2

PEDF

Osteopontin

CRP

PAI-1 Active

bFGF

PlGF

TGFβ1

Gro-α

PAI-1 Total

HGF

VEGF-A

TGFβ2

ICAM-1

P-selectin

IGF-1

VEGF-C

sTGFβRIII

IL-6

SDF1

IGFBP1

VEGF-D

TSP2

IL-8

VCAM-1

IGFBP3

sVEGFR1

 

MCP-1

 

PDGF-AA

sVEGFR2

   

PDGF-BB

    
  1. ANG-2 = angiopoietin-2; bFGF = basic fibroblast growth factor; HGF = hepatocyte growth factor; IGF-1 = insulin-like growth factor-1; IGFBP = insulin-like growth factor-binding protein; PDGF = platelet-derived growth factor; PEDF = pigment epithelium-derived factor; PlGF = placental growth factor; VEGF = vascular endothelial growth factor; sVEGFR = soluble vascular endothelial growth factor receptor; TGFβ = transforming growth factor beta; sTGFβRIII = soluble transforming growth factor beta receptor type III; TSP = thrombospondin; CRP = c-reactive protein; PAI-1 = plasminogen activator inhibitor-1; Gro-α = growth regulated oncogene-alpha; ICAM-1 = intercellular adhesion molecule 1; IL = interleukin; MCP-1 = macrophage chemoattractant protein-1; SDF1 = stromal cell-derived factor-1; VCAM-1 = vascular cell adhesion molecule 1.