Table 2 Regulated proteins in BTZ and CFZ groups at different time points (n.s. nonsignificant).
From: Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib
Protein Name | Regulation in BTZ group compared to CONT group | p value (BTZ vs CONT) | Regulation in CFZ group compared to CONT group | p value (CFZ vs CONT) |
|---|---|---|---|---|
Regulated Proteins Following 24 h | ||||
Stress-70 protein | Up regulated | 0.003 | n.s. | — |
Superoxide dismutase [Mn] | Up regulated | 0.017 | n.s. | — |
Protein disulfide-isomerase A3 | Up regulated | 0.045 | n.s. | — |
Heat shock protein HSP 90-alpha | Up regulated | 0.045 | Up regulated | 0.001 |
Ubiquitin-like modifier-activating enzyme 1 | Down regulated | 0.014 | Down regulated | 0.013 |
Microtubule-associated protein | Down regulated | 0.012 | n.s. | — |
Regulated Proteins Following 3 h | ||||
Catalase | n.s. | — | Up regulated | 0.031 |
Regulated Proteins Following 48 h | ||||
Caprin-1 | Down regulated | 0.034 | n.s. | — |
60 kDa heat shock protein (mt) | n.s. | — | Up regulated | 0.031 |
Lamin B1 | n.s. | — | Down regulated | 0.0001 |
14-3-3 protein epsilon | Up regulated | 0.022 | n.s. | — |
Protein disulfide-isomerase A6 | Up regulated | 0.043 | n.s. | — |
