Figure 2

(A) High-resolution computational model simulation of brain current flow during tDCS. The “M1-SO” assembly was simulated by sponge with anode positioned vertically over 10–20, location C3, and cathode positioned horizontally on the contralateral-supraorbital, approximately over 10–20, location Fp2. (B) Current flow patterns on a slice (A/m²). The model predicted electric field maps generated in outer cortical regions. Our results show diffuse and clustered brain current flow that includes left motor regions, as well as other regions implicated in treatment of pain and other regions of interest. (in V/m: M1 ipsilateral 0.23, contralateral 0.15, left DLPFC 0.23, nucleus accumbens 0.22, and cingulate 0.25). (C) Consecutive coronal slices and brain current flow.