Figure 2 | Scientific Reports

Figure 2

From: Receptor-Ligand Interaction Mediates Targeting of Endothelial Colony Forming Cell-derived Exosomes to the Kidney after Ischemic Injury

Figure 2

ECFC exosome biodistribution by optical imaging. Representative IVIS images in a live mouse (a) and in dissected organs (b) 30 min after injection of 20 μg DiR-labeled exosomes. Sham+EX (sham mice treated with exosomes), IR+EX (mice subjected to 30 min of kidney ischemia followed by infusion of exosomes). Graphs depict the fold-change in fluorescence between Sham+EX and IR+EX mice in the region of interest (ROI) (a) and in kidneys and other dissected organs at 30 min, 4 hrs and 24 hrs after DiR-exosome injection (b). *P < 0.01 vs Sham + EX by Student t-test (a) or one-way ANOVA (b) n = 4.

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