Figure 3

Exosomes selectively increase miR-486-5p levels in kidneys. Semi-quantitative analysis of miR-486-5p levels in organs of interest 30 min, 4 hrs and 24 hrs post-reperfusion. Sham (untreated mice), IR (mice with 30 min of bilateral kidney ischemia) and IR + EX (mice with 30 min of bilateral kidney ischemia followed by infusion of 20 μg of exosomes). *P < 0.01 vs Sham or IR, +P < 0.05 vs Sham, by one-way ANOVA, n = 4.