Figure 3

Typical experimental setup for in vitro and in vivo measurements. (A) Full experimental configuration of the Corticonic board (1). Connected to the board there are: the in vitro UF-MEA (2), the ground (3), the reference (4), the stimulation outputs (5) and the USB cable (6). (B) Placement of the in vitro UF-MEA on a cortical slice. Electrodes span across deeper and upper layers (DL and UL, respectively). Electrodes and via holes are indicated with red arrows. (C) In vivo 32-channel hemispheric UF-MEA placed on the cortex of a mouse, covering one hemisphere and spanning across different cortical regions. (D) Areas over which the array lays on while on the mouse cortex: PtA, parietal association; RSD, retrosplenial dysgranular cortex; SOM, somatosensory.