Figure 4 | Scientific Reports

Figure 4

From: An ultra-compact integrated system for brain activity recording and stimulation validated over cortical slow oscillations in vivo and in vitro

Figure 4

Signal-to-noise ratio (SNR) analysis for the Corticonic system. (A) Representative local field potential (LFP) traces recorded during the three different configurations. Configuration 1 (blue): conventional recording system and conventional MEA; Configuration 2 (green): Corticonic recording system + conventional MEA; Configuration 3 (yellow): Corticonic recording system and in vitro UF-MEA. (B) Averaged spectral SNR across all channels and experiments for the three different configurations across the full frequency spectrum below 1500 Hz. Colored shade: standard error. (C) Average of the area under the curve (AuC) of spectral SNR curves below 1500 Hz for the different configurations. (D) Average of voltage SNR for the three configurations. C + D: Mann-Whitney U test; *p < 0.05, **p < 0.01, ***p < 0.001; data shown as mean ± standard error.

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