Figure 1 | Scientific Reports

Figure 1

From: Increased frequency of systemic pro-inflammatory Vδ1+ γδ T cells in HIV elite controllers correlates with gut viral load

Figure 1

Vδ1+ cells expanded in HIV-infected white subjects, despite controlled viremia. PBMCs were assessed by flow cytometry and viable CD3+ cells were analyzed for expression of Vδ1 and Vδ2. (a) Representative flow plots from an HIV- uninfected subject (Neg) and an elite controller (EC) are shown. The numbers in the quadrants represent the percentage of total CD3+ cells. (b) Summary data showing the median percentage of viable CD3+ cells that are Vδ1+ for Neg (n = 17), EC (n = 15), chronic treated (CT; n = 13), viremic controller (VC; n = 4), and chronic untreated (CU; n = 11) subjects. The medians of the cohorts were significantly different (p < 0.0001) as assessed by the Kruskal-Wallis test. Dunn’s multiple comparison tests were used to assess differences between Neg and each HIV- infected group. *p < 0.05; **p < 0.01; ***p < 0.001.

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