Table 2 Top up-regulated gene-sets in horses with asthma following challenge, ranked according to FDR.

From: Gene set enrichment analysis of the bronchial epithelium implicates contribution of cell cycle and tissue repair processes in equine asthma

Name of gene set

Size of gene set

NES^

FDR*

Rank at max

M phase - reactome - react_910.4

213

2.68

<0.001a

1633

Cell cycle, mitotic - reactome - react_152.7

373

2.67

<0.001a

1633

Mitotic metaphase and anaphase - reactome - react_150314.2

150

2.64

<0.001a

1624

Cell cycle - reactome - react_115566.4

430

2.63

<0.001a

1633

Mitotic nuclear division - gobp - go:0007067

126

2.61

<0.001a

1016

Mitotic anaphase - reactome - react_1275.3

149

2.60

<0.001a

1624

Nuclear division - gobp - go:0000280

168

2.59

<0.001a

1016

Separation of sister chromatids - reactome - react_150471.2

141

2.58

<0.001a

1624

Mitotic prometaphase - reactome - react_682.3

96

2.54

<0.001a

1515

Chromosome segregation - gobp - go:0007059

129

2.54

<0.001a

1186

  1. ^Normalized enrichment score.
  2. *False discovery rate.
  3. aExact FDR value not detected (<1/maximum number of permutations).
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