Table 3 Top up-regulated gene-sets in non-asthmatic horses following challenge, ranked according to lowest rank at maximum score.

From: Gene set enrichment analysis of the bronchial epithelium implicates contribution of cell cycle and tissue repair processes in equine asthma

Name of gene set

Size of gene set

NES^

FDR*

Rank at max

Mitotic cytokinesis - gobp - go:0000281

25

1.99

2.91E-04

286

Negative regulation of protein binding - gobp - go:0032091

34

2.005

2.39E-04

288

Cytoskeleton-dependent cytokinesis - gobp - go:0061640

30

1.96

8.31E-04

288

Negative regulation of binding - gobp - go:0051100

58

1.87

7.87E-03

288

Aurora a signaling - pathway interaction database nci-nature curated data - aurora a signaling

25

1.84

1.36E-02

288

Regulation of protein binding - gobp - go:0043393

71

1.77

3.87E-02

288

Condensed nuclear chromosome - gocc - go:0000794

29

1.75

4.49E-02

288

Microtubule cytoskeleton organization involved in mitosis - gobp - go:1902850

24

1.75

4.35E-02

291

Condensed chromosome, centromeric region - gocc - go:0000779

26

1.94

1.46E-03

319

Regulation of leukocyte chemotaxis - gobp - go:0002688

48

1.82

1.98E-02

347

  1. ^Normalized enrichment score.
  2. *False discovery rate.