Table 6 Most enriched transcription factor motifs among significantly up- and down-regulated genes in horses without asthma following challenge.
Transcription factor motif ID | NES | Transcription factors |
|---|---|---|
Up-regulated genes | ||
jaspar-MA0314.1 | 6.01 | NFYB, POLE3, NFYC, NFYA |
yetfasco-1536 | 5.73 | NFYB, POLE3, NFYA, NFYC |
homer-M00123 | 5.58 | RELA, NFKB2, REL, NFKB1, BCL3, OVOL2, STAT6, EBF1 |
taipale-RRGGTCAAAGTCCRNN-HNF4A-DBD | 5.49 | HNF4A, NR2F1, NR2F2, HNF4G, RXRG, PPARG, RXRB, RXRA, NR2C2 |
jaspar-MA0316.1 | 5.27 | NFYC, POLE4, NFYA, NFYB |
transfac_public-M00288 | 5.27 | NFYB, NFYA, POLE3, NFYC |
elemento-CTGGCCA | 5.23 | N/A |
yetfasco-1537 | 5.19 | NFYC, POLE4, NFYA, NFYB |
jaspar-MA0060.1 | 5.09 | NFYA, NFYB, NFYC, YBX1, POLE3, POLE4 |
transfac_public-M00287 | 4.91 | NFYA, NFYB, NFYC, YBX1, POLE3, POLE4 |
Down-regulated genes | ||
Taipale-SGTTGCYARGCAACS-RFX4-DBD | 5.77 | RFX4, RFX3, RFX2#, RFX1 |
Transfac_pro-M00481 | 5.67 | AR, PGR, NR3C1, NR3C2 |
Factorbook-NR3C1 | 5.39 | NR3C1, AR, PGR, NR3C2, HSF1 |
Yetfasco-658 | 5.38 | |
Transfac_pro-M02789 | 5.17 | RFX4, RFX5, RFX7 |
Taipale-RRGWACANNNTGTWCYY-AR-DBD | 5.15 | AR, NR3C1, NR3C2, PGR |
Transfac_pro-M02465 | 4.96 | HMGB4, TOX, TOX2, TOX4, TOX3, TBP, TBPL2, TBPL1 |
Transfac_pro-M02790 | 4.82 | RFX7, RFX5 |
Transfac_pro-M01201 | 4.77 | AR, NR3C1, PGR, NR3C2 |
Swissregulon-AR.p2 | 4.75 | AR, PGR, NR3C1, NR3C2, HSF1 |
