Figure 3

Representative data of LV ESPVR and EDPVR (a), and VO₂–PVA relationship (b) at 32 °C (hypothermia, n = 10), 37 °C (normothermia, n = 13), and 42 °C (hyperthermia, n = 10). The ESPs and EDPs data were recorded at each fixed LV volume in hypo-, normo-, and hyperthermia. (a) As shown by a dashed long arrow in the left panel, LV ESPVR shifted downward (a), and LV EDPVR ained unchanged, but VO₂–PVA relationship could be superimposed; neither slope nor VO₂ intercept changed (b) with increasing cardiac temperature. Thus, each data point of VO₂–PVA at each LVV shifted left-downward with increasing cardiac temperature (a dashed long arrow in the right panel) from hypothermia (solid triangle) to hyperthermia (solid square) passing through normothermia (solid circle) on the superimposable VO₂–PVA relationship line. As shown by a dashed open circle in the right panel (b), unchanged VO₂ intercepts indicate that PVA-independent VO₂ were not affected by changing cardiac temperature.