Figure 4
Comparison of the mean slopes (O2 costs of PVA) (a), VO2 intercepts (PVA independent VO2) (b), O2 consumption for basal metabolism per minute (c), VO2 for excitation–contraction (E-C) coupling (d), O2 costs of LV contractility for Ca2+ (e), and CBF (f) at 32 °C (hypothermia, n = 10), 37 °C (normothermia, n = 13), and 42 °C (hyperthermia, n = 10). CBF in hyperthermia is significantly smaller than that in hypothermia, which may be related to lower LV contractility (LVV = 0.16, balloon material volume = 0.08 ml plus balloon water volume = 0.08 ml). We confirmed no lactate production in the heart through the experiments, indicating ischemia was not induced. Values are presented as means ± SD. *p < 0.05 vs. 32 °C, †p < 0.05 vs. 37 °C.
