Figure 2
From: Extensions to Michaelis-Menten Kinetics for Single Parameters

The relationship between variables. (a) The illustration of the cyclic nature of forming enzymes from substrates, enzyme-substrate complexes, and products. This also shows thermodynamically heterogeneous reactions while kinetically homogenous behaving in a close loop cycle. It coincides with steps in equation (6), where S = substrate (A), E + R = substrate + reactants (B), E + S = enzymes + substrates (C), ES = enzyme-substrate complexes (D), and E + P = enzymes + products (E) (b) Defining of v. The relationships between the variables dv, d[S], and t in equation (21). In which the progressive increment of v with time is enveloped with the heterogeneous substrate increases of d[S]. The substrate concentration increases from S1 to S2 for the time duration from t1 to t2, corresponding to intersects of v1 and v2.