Figure 3 | Scientific Reports

Figure 3

From: High-throughput neutralization assay for multiple flaviviruses based on single-round infectious particles using dengue virus type 1 reporter replicon

Figure 3

Comparison of ZIKV-SRIP and ZIKV in a neutralization test using three Zika NS1 IgG-positive human serum (#66, #69, and #70), one serum from normal healthy donor, and anti-E monoclonal antibody. Serum samples were serially four-fold diluted and incubated with ZIKV-SRIP or authentic ZIKV overnight at 4 °C. The mixture was then titrated on Vero cells. Dose-dependent percentage reduction curves were obtained with ZIKV-SRIP (open circles) and ZIKV virus (closed square).

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