Figure 4

γδ T cell subsets in LCH. (a) Gating strategy for identifying γδ T cell subsets. (b) Proportions of CD4⁺CD8⁻, CD8⁻CD4⁻ and CD8⁺CD4⁻ cells in γδ T cells from the peripheral blood from healthy donors (HD) and patients with LCH (PB) and in lesional γδ T cells from patients with active LCH. (c) Proportions of CD8⁻CD161⁺, CD8⁺CD161⁺, CD8⁺CD161⁻ and CD8⁻CD161⁻ cells in γδ T cells from the peripheral blood from healthy donors (HD) and patients with LCH (PB) and in lesional γδ T cells from patients with active LCH. Kruskal-Wallis tests with Dunn’s multiple comparisons were conducted for (b,c), error bars indicate median + interquartile range.