Table 1 Effects of AADF on haematological parameters with DOX-induced hepatoxicity.*P < 0.05 and **P < 0.01 vs. DOX + saline group.

From: Amino acid modified [70] fullerene derivatives with high radical scavenging activity as promising bodyguards for chemotherapy protection

Parameter

Groups

Control

DOX + Saline

DOX + C70-Lys

DOX + C70-Ala

DOX + VC

WBC (×109/L)

5.31 ± 1.27

4.33 ± 0.72

4.45 ± 0.66*

4.36 ± 0.57

4.40 ± 0.99

RBC (×1012/L)

7.31 ± 0.95

5.73 ± 0.39

7.15 ± 1.68**

6.05 ± 0.92*

5.82 ± 0.63

HGB (g/L)

121.25 ± 14.36

95.75 ± 5.74

119.50 ± 9.19**

109.67 ± 18.77*

97.67 ± 12.02

HCT (%)

39.63 ± 4.30

28.43 ± 2.34

37.55 ± 5.43**

33.43 ± 7.09*

28.05 ± 2.90

PLT(×109/L)

567.75 ± 87.17

741.67 ± 45.54

582.67 ± 57.74**

595.75 ± 52.82**

735.25 ± 78.79

Neutrophil (%)

17.60 ± 3.35

22.60 ± 3.52

15.70 ± 3.30**

18.75 ± 1.44*

24.27 ± 3.93

Lymphocyte (%)

81.82 ± 6.90

73.92 ± 3.67

81.63 ± 4.25**

75.86 ± 4.01

72.75 ± 3.17

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