Figure 5
CD40L enhances antibody-induced protection. (A) Schematic diagram of the animal study timeline. Passive serum transfer was done from immunized and challenged donor mice into naïve recipient mice. (B) Four days post-challenge, lungs from the recipient mice were collected for viral titer determination using plaque assay. Serum from Ad-SF40L immunized mice resulted in the highest lung viral clearance in recipients. Data shown is mean ± SEM representative of 2 independent experiments; n = 4 per group; *p < 0.05 (one-way ANOVA with Bonferroni posttest).
