Table 4 Results of receiver operating characteristic analysis for each single potential biomarker and the multivariate biopattern for differentiating sepsis requiring care in pediatric intensive care from sepsis cared for in the emergency department.
From: Biomarker Phenotype for Early Diagnosis and Triage of Sepsis to the Pediatric Intensive Care Unit
Potential biomarkers | AUROC ± standard error | |
|---|---|---|
1–23 month old cohort | 2–17 year old cohort | |
3-Hydroxyisovalerate | 0.65 ± 0.05 | 0.71 ± 0.04 |
3-Methyl-2-oxovalerate | 0.64 ± 0.06 | 0.62 ± 0.04 |
Acetate | 0.73 ± 0.05 | 0.86 ± 0.03 |
Alanine | 0.84 ± 0.04 | 0.75 ± 0.04 |
Dimethylamine | 0.79 ± 0.04 | 0.77 ± 0.04 |
Mannose | 0.75 ± 0.05 | 0.80 ± 0.03 |
O-Acetylcholine | 0.76 ± 0.05 | 0.75 ± 0.04 |
Multivariate biopattern | 0.91 ± 0.03 | 0.93 ± 0.02 |
