Table 2 Normalized values of flexion, extension, lateral bending and axial rotation in CD-canine treated IVD segments.

From: NTG-101: A Novel Molecular Therapy that Halts the Progression of Degenerative Disc Disease

Biomechanical Characteristics

NTG-101 Range (Mean ± SD) (rad)

PBS (1X) Range (Mean ± SD) (rad)

Flexion

0.50–0.88 (0.78 ± 0.19)

1.21–1.99 (1.59 ± 0.39)

Extension

−0.49–0.22 (−0.12 ± 0.3)

−0.061–0.01 (−0.02 ± 0.04)

Lateral bending

   Left

0.35–1.14 (0.88 ± 0.36)

0.81–1.91 (1.43 ± 0.56)

   Right

0.00–0.24 (0.08 ± 0.11)

−0.12–−0.04 (−0.07 ± 0.04)

Axial Rotation

   Left

−0.14–−0.05 (−0.01 ± 0.04)

−0.20–−0.07 (−0.15 ± 0.07)

   Right

0.12–0.39 (0.24 ± 0.11)

0.21–0.53 (0.41 ± 0.17)