Figure 8
From: GBF1 and Arf1 interact with Miro and regulate mitochondrial positioning within cells
The inhibition of GBF1 induces a condensation and a change of morphology of mitochondria. RPE1 cells were incubated with either GCA (10 μM) or DMSO alone (control) for 1h30 and juxta-nuclear regions were imaged by electron tomography, followed by segmentation of mitochondria (blue), microtubules (red) and the nucleus (pink). (A,C): control cells. (B,D): GCA-treated cells. (A,B): segmentation of longitudinal RPE1 cell sections overlayed on a central tomographic slice, (C,D): segmentation of cross sections of RPE1 cells. Bar = 0.5 µm.
