Figure 8
(A) Redundancy Analysis (RDA) plot representing microbial ecology of young (10 week-old) mice (black cluster), 8 months (yellow cluster), 13 months (blue cluster), 15 months (green cluster) and 19 months (brown cluster) in the faeces. The different ages were used as explanatory variables for the RDA, where the 10-week-old and 13-month-old variables had significantly different microbial compositions (Monte Carlo permutation test; P < 0.05). (B) Heatmap showing the abundance fold-change of bacteria with age. In red, bacteria which are significantly more abundant in faeces and in blue the bacteria that are less abundant. Scale: Log2(Fold Change) = −1 (blue) <0 (white) <1 (red). The intensity of the colour is proportional to change in bacterial presence.
