Table 2 Soluble markers of inflammation in plasma in the “rifaximin” (Rif, n = 20) and in the “no intervention” group (No Int, n = 20).

From: RETRACTED ARTICLE: Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency

Marker

Group

Baselinea (n = 40)

2 weeksa (n = 38)

8 weeksa (n = 30)

P value interactionb

CRPmg/L

No Int

3.5 (2.1–7.1)

4.7 (1.0–7.9)

3.2 (2.5–6.9)

0.029

Rif

1.9 (0.86–4.80)

2.20 (1.2–4.8)

2.8 (1.9–5.4)*

sCD14ng/mL

No Int

3949 (3162–4456)

4032 (3290–4630)

3826 (2978–4459)

0.555

Rif

3378 (3072–4219)

3639 (3241–4414)

3552 (2921–4485)

LPSpg/ml

No Int

83 (78–91)

86 (78–92)

87 (78–94)

0.955

Rif

87 (80–96)

90 (78–98)

90 (83–102)

sCD25ng/mL

No Int

1.44 (0.71–2.10)

1.54 (0.74–1.89)

1.33 (0.80–1.86)

0.636

Rif

0.65 (0.51–1.43)

0.63 (0.54–1.18)

0.99 (0.44–1.55)

sCD163ng/mL

No Int

1699 (1350–2001)

1677 (984–1930)

1536 (1194–1940)

0.320

Rif

971 (647–1353)

902 (749–1310)

1151 (793–1549)

Neopterinnmol/L

No Int

11.18 (9.40–21.60)

13.17 (8.32–24.31)

10.37 (8.11–21.90)

0.058

Rif

9.02 (6.71–14.65)

7.79 (6.37–17.24)

11.43 (6.66–21.78)

  1. aData are given in median (25–75 percentile). bThe p value reflects the interaction between time and group from UNIANOVA. *P < 0.05 vs. baseline.