Figure 1 | Scientific Reports

Figure 1

From: A novel fluorescein-bisphosphonate based diagnostic tool for the detection of hydroxyapatite in both cell and tissue models

Figure 1

Selectivity towards calcium minerals of Fluorescein-BP (1) in comparison to Alizarin S stain (2). Calcium minerals were incubated with Fluorescein-BP (5 μM) (A) or 1% w/w Alizarin S (B) in water for 2 hours and the un-bound probe was removed and quantified. The histograms show the relative amounts of bound fluorophore for each of the calcium minerals. Data shown are representative of at least 3 independent experiments yielding comparable results. *P < 0.05, **P < 0.01, ***P < 0.001 compared to HAP, n = 6.

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