Figure 4
From: Multimodal assessments of Zika virus immune pathophysiological responses in marmosets
Immune-phenotyping of ZIKV-infected marmoset whole blood. Immune cell changes (up to 30 dpi) were determined at each time-point with flow cytometry. (A) Four main immune subsets (B cells, CD8+ T cells, HLA-DR+ NK cells and CD16+ monocytes) which displayed significant differences between ZIKV-infected (n = 6) and non-infected (n = 5) marmosets are shown. Data is presented as fold change relative to baseline (−7dpi) value. (B) Flow cytometry data were further visualized by tSNE to identify the specific differences (based on spatial distribution) between the immune subsets shown in (A). Data are plotted as mean ± SD. *P < 0.05 by non-parametric Mann Whitney test, two tailed.
