Figure 4 | Scientific Reports

Figure 4

From: Modified VEGF-A mRNA induces sustained multifaceted microvascular response and accelerates diabetic wound healing

Figure 4The alternative text for this image may have been generated using AI.

Repeated and higher doses of AZD8601 had greater effects on diabetic wound healing. (A) Dosing on days 0 and 3 increased early healing compared to dosing on day 0 only (n = 7–8/group). (B) The greatest effect on wound closure was achieved by the 200 µg dose of AZD8601, which came closest to replicating the effect of exogenous recombinant VEGF-A165 protein positive control (n = 6/group). *p < 0.05, **p < 0.01, ***p < 0.001.

Back to article page