Table 5 Pathways Analysis of Genes with dysregulated DMPs.

From: Genome-wide DNA methylation changes in CD19+ B cells from relapsing-remitting multiple sclerosis patients

Pathway (BioSystems)

Source

No. of genes

FDR P-value

Neutrophil degranulation

REACTOME

138

9.20E-10

Innate Immune System

REACTOME

293

4.08E-09

Hematopoietic cell lineage

KEGG

40

8.88E-07

Hemostasis

REACTOME

150

3.16E-05

Extracellular matrix organization

REACTOME

80

1.54E-04

Signalling events mediated by focal adhesion kinase

Pathway Interaction Database

24

1.97E-04

Phospholipase D signalling pathway

KEGG

46

3.31E-04

B cell receptor signalling pathway

KEGG

28

3.31E-04

Regulation of RAC1 activity

Pathway Interaction Database

19

3.82E-04

Cytokine Signalling in Immune system

REACTOME

166

4.14E-04