Figure 6 | Scientific Reports

Figure 6

From: Safety evaluation of frequent application of microbubble-enhanced focused ultrasound blood-brain-barrier opening

Figure 6

Quantification of TUNEL assay and GFAP expression. (A) Percentage of TUNEL positive cells. FUS-BBB opening protocols using excessive MB concentration results in statistically significant increase of cellular apoptosis. Also the combination of excessive MB with excessive FUS exposure results in cumulative ell damage. (B) Average number of activated astrocyte per 100 cells. In both normal MB and excessive MB group FUS-BBB opening induced astrocyte activation. n = 6. *p < 0.05.

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