Table 1 Antibacterial activity of IMB-T130 against the M. smegmatis strains with a vector control or overexpressing plasmid for MtDHQS and MtL12 genes.
From: IMB-T130 targets 3-dehydroquinate synthase and inhibits Mycobacterium tuberculosis
Control vector (PMV261 plasmid) | Overexpressing MtDHQS | Overexpressing MtL12 | |
|---|---|---|---|
IMB-T130 | 0.312 μg/ml | 2.5 μg/ml | 0.312 μg/ml |
Streptomycin | 0.156 μg/ml | 0.156 μg/ml | 0.156 μg/ml |
