Table 5 Fixed effects using linear mixed models.

From: Quantitative DNA Methylation Analysis of DLGAP2 Gene using Pyrosequencing in Schizophrenia with Tardive Dyskinesia: A Linear Mixed Model Approach

Group

Num DF

Den DF

F/t value

p value

TD vs. NTD vs HC

2

101

6.26

0.0027

   Site

2

206

871.4

<0.0001

   Site 1 vs 3

  

−6.20

<0.0001

   Site 2 vs 3

  

−38.5

<0.0001

TD vs HC

1

67

8.78

0.0042

   Site

2

136

457.74

<0.0001

   Site 1 vs 3

  

−4.51

<0.0001

   Site 2 vs 3

  

−28.16

<0.0001

NTD vs HC

1

67

6.22

0.0151

   Site

2

136

501.15

<0.0001

   Site 1 vs 3

  

−4.73

<0.0001

   Site 2 vs 3

  

−29.48

<0.0001

TD + NTD vs HC

1

102

12.18

0.0007

   Site

2

206

870.49

<0.0001

   Site 1 vs 3

  

−6.20

<0.0001

   Site 2 vs 3

  

−38.83

<0.0001

TD vs NTD

1

68

0.62

0.436

   Site

2

138

1050.4

<0.0001

   Site 1 vs 3

  

−6.74

<0.0001

   Site 2 vs 3

2

138

−42.63

<0.0001

  1. Abbreviations: TD = schizophrenia patients with tardive dyskinesia (TD), NTD = schizophrenia patients without TD, HC = healthy controls, Num DF refers to the number of degrees of freedom in the model, Den DF refers to the number of degrees of freedom associated with the model errors, F/t value and p value are based on the linear mixed models.
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