Table 1 GO terms significantly enriched in the edge mantle.

Upregulated in diseased scallops

Related to cellular motility

Related to calcium ion

GO:0005929

cilium

2.29E-12

C

GO:0060402

calcium ion transport into cytosol

6.53E-04

P

GO:0005874

microtubule

8.31E-11

C

GO:0005509

calcium ion binding

8.02E-04

F

GO:0031514

motile cilium

1.49E-10

C

GO:0051480

cytosolic calcium ion homeostasis

2.81E-03

P

GO:0003777

microtubule motor activity

2.89E-08

F

GO:0005262

calcium channel activity

5.00E-02

F

GO:0005930

axoneme

4.39E-08

C

Related to shell organic matrix

GO:0003341

cilium movement

8.41E-08

P

GO:0018392

glycoprotein 3-alpha-L-fucosyltransferase activity

1.88E-03

F

GO:1990716

axonemal central apparatus

1.08E-07

C

GO:0030203

glycosaminoglycan metabolic process

1.40E-02

P

GO:0035082

axoneme assembly

6.89E-07

P

Related to nervous system

GO:0030286

dynein complex

1.42E-06

C

GO:0021591

ventricular system development

4.77E-05

P

GO:0060294

cilium movement involved in cell motility

1.27E-05

P

GO:0021670

lateral ventricle development

1.15E-04

P

GO:0003351

epithelial cilium movement

3.22E-05

P

GO:0043083

synaptic cleft

4.64E-04

C

GO:0036158

outer dynein arm assembly

3.22E-05

P

GO:0007399

nervous system development

4.75E-04

P

GO:0036157

outer dynein arm

5.83E-05

C

GO:0010976

positive regulation of neuron projection development

2.96E-03

P

GO:0010632

regulation of epithelial cell migration

6.79E-05

P

GO:0007420

brain development

4.64E-03

P

GO:0007018

microtubule-based movement

9.43E-05

P

GO:0007417

central nervous system development

4.68E-03

P

GO:0060271

cilium morphogenesis

4.77E-04

P

GO:0006665

sphingolipid metabolic process

7.02E-03

P

GO:0036064

ciliary basal body

6.35E-04

C

GO:0045202

synapse

1.76E-02

C

GO:0042384

cilium assembly

1.09E-03

P

GO:0043005

neuron projection

3.21E-02

C

GO:0036156

inner dynein arm

1.50E-03

C

GO:0005328

neurotransmitter:sodium symporter activity

1.39E-02

F

GO:0001539

cilium or flagellum-dependent cell motility

2.32E-03

P

Related to energy metabolism

GO:0005858

axonemal dynein complex

2.81E-03

C

GO:0004550

nucleoside diphosphate kinase activity

3.94E-08

F

GO:0036159

inner dynein arm assembly

2.81E-03

P

GO:0006165

nucleoside diphosphate phosphorylation

3.62E-06

P

GO:0008017

microtubule binding

1.54E-02

F

GO:0009142

nucleoside triphosphate biosynthetic process

2.08E-05

P

GO:0072372

primary cilium

3.60E-02

C

GO:0016887

ATPase activity

2.58E-03

F

GO:0030334

regulation of cell migration

3.84E-02

P

GO:0004396

hexokinase activity

1.15E-04

F

GO:0019158

mannokinase activity

1.15E-04

F

Downregulated in diseased scallops

GO:0004340

glucokinase activity

3.13E-04

F

Related to nervous system

GO:0006000

fructose metabolic process

3.13E-04

P

GO:0043523

regulation of neuron apoptotic process

2.40E-03

P

GO:0008865

fructokinase activity

3.13E-04

F

Related to immume system

GO:0016051

carbohydrate biosynthetic process

5.06E-04

P

GO:0006954

inflammatory response

2.07E-03

P

GO:0005536

glucose binding

6.53E-04

F

GO:0051607

defense response to virus

6.20E-03

P

GO:0001678

cellular glucose homeostasis

8.86E-04

P

GO:0045087

innate immune response

1.00E-02

P

GO:0051156

glucose 6-phosphate metabolic process

8.86E-04

P

GO:0005044

scavenger receptor activity

1.31E-02

F

GO:0006013

mannose metabolic process

4.67E-03

P

GO:0006006

glucose metabolic process

2.64E-02

P