Table 2 Results of one-way analysis of covariance in plasma NFL levels after adjusting age, sex, years of education, and APOE ɛ4 carrier status.

From: Levels of plasma neurofilament light chain and cognitive function in patients with Alzheimer or Parkinson disease

Parameter

B

SE

t value

P value

Intercept

0.454

0.171

2.661

0.008

Age

0.013

0.002

6.591

<0.001

Sex

−0.039

0.026

−1.504

0.134

Years of education

0.003

0.003

1.068

0.286

APOE ε4 carrier

0.027

0.029

0.918

0.359

Control

−0.201

0.034

−5.954

<0.001

MCI

−0.141

0.033

−4.254

<0.001

PDND

−0.225

0.048

−4.676

<0.001

PDD

−0.096

0.048

−1.996

0.047

AD

Ref

   
  1. Dependent variable: plasma NFL level (log transformation).
  2. NFL, neurofilament light chain; APOE, apolipoprotein E; SE, standard error; MCI, mild cognitive impairment; PDND, non-demented Parkinson’s disease; PDD, Parkinson’s disease dementia; AD, Alzheimer’s disease.