Figure 4

Pharmacokinetics of modified MHP1-Ac or MHP1-AcN after intravenous injection post-cerebral ischemia. MHP1-Ac or MHP1-AcN were intravenously injected 4 h after tMCAo. Although MHP1-Ac was quickly degraded in plasma, approximately 8000 ng/ml of MHP1-AcN was preserved at 30 min after injection.