Figure 4
From: Streptococcus mitis Expressing Pneumococcal Serotype 1 Capsule
Opsonophagocytosis killing (OPK) testing of S. mitis and serotype 1 S. pneumoniae isolates using anti-serotype 1 pneumococcal and non-pneumococcal serum. Serotype 1 S. pneumoniae = positive control; S. mitis ATCC (NCTC 12261) strain confirmed to be wzy1-negative = negative control. Antibody source for OPK assay: 007 S. pneumoniae human reference serum. Complement: baby rabbit complement; OPK titer: reciprocal of serum dilution with >50% growth compared to serum free complement control. (S. mitis strain L006 and L121 representing two distinct S. mitis clones tested). Error bars represent the lower and upper limit of OPK titer based on the test runs.
