Figure 6
From: Proof of concept study of mass cytometry in septic shock patients reveals novel immune alterations
PD1 expressing CD4 T cells show high heterogeneity after septic shock and do not co-express other immune checkpoint inhibitors. Expressions of several exhaustion (A) and activation (B) markers on CD4 T cell nodes from SPADE were compared in septic shock patients (n = 4, dark grey boxes) and healthy volunteers (n = 5, white boxes). The light grey areas represent global median expression on CD4 T cells from mass-minus-one control, characterising the threshold of positive expression for each marker. PD-1 expressing nodes are highlighted underlined.
