Figure 7
The anti-tumor effects and phase contrast microscope photos of cytotoxicity assay of native α-MC or mono-PEGylated on the proliferation of Hela, MDA-MB-231 and A549 cells for 72 h. (A–C) Indicated the dose-dependent inhibition of the proliferation of Hela, MDA-MB-231 and A549 cells by native and mono-PEGylated α-MC at different concentrations. Value represented the mean ± SD of three independent experiments. *P < 0.5 compare with α-MC. (D) Indicated phase contrast microscope photos of cytotoxicity assay (200x);(a) reflected the normal control of Hela, MDA-MB-231 and A549 cells; (b) reflected Hela, MDA-MB-231 and A549 cells treated with 0.5 mg/mL of α-MC; (c) reflected Hela, MDA-MB-231 and A549 cells treated with 0.5 mg/mL of mono-PEGylated α-MC.
