Table 1 Number of differentially expressed small non-coding RNAs (adjusted p-value < 0.001).

From: Circulating small non-coding RNAs associated with age, sex, smoking, body mass and physical activity

 

Nu. of sncRNAs

Age, categorical N = 520

Age**, N = 520

Blood donor group N = 378

Body mass N = 343

Body mass + age N = 343

Body mass** + age N = 343

Sex N = 459

Sex + age N = 459

PA N = 293

PA + age N = 293

Smoking N = 298

smoking + age N = 298

isomiRs

3376

26

117

3

7

26

30

4

21

0

17

2

18

tRF

3779

1

157

0

0

28

3

0

27

0

10

0

0

lncRNA

2974

30

69

0

5

43

25

3

53

0

24

0

31

miRNA

378

11

26

0

0

0

0

0

11

0

0

1

2

mRNA fragments

15217

428

807

0

23

257

137

22

265

4

144

0

108

piRNA

582

6

29

0

3

24

54

1

59

0

7

0

3

snoRNA

59

1

59

0

1

1

1

1

4

0

0

0

5

snRNA

196

48

32

0

5

5

23

0

1

0

1

8

12

tRNA

486

3

15

0

0

27

39

2

6

1

5

0

3

Total

27251

554

1311

3

44

411

312

33

447

5

208

11

182

  1. The number of significantly (p-value adjusted for multiple testing <0.001) differential expressed sncRNAs associated with age, body mass, blood donor group, sex, physical activity (PA) and smoking. Age and body mass (BMI) were tested as categorical and continuous variables, marked with **. Number of samples in each analysis are shown in the top row. Age significantly influenced expression, thus the number of RNA molecules associated with body mass, physical activity and smoking were also presented with age adjustment.