Table 3 Genes that were significantly upregulated or downregulated between study day 1 and 14 (global p value for the pathway ≤ 0.05).

From: Differential Gene Expression in Peripheral White Blood Cells with Permissive Underfeeding and Standard Feeding in Critically Ill Patients: A Descriptive Sub-study of the PermiT Randomized Controlled Trial

Pathway

Global p-value

Number of up- or downregulated genes

Total number of genes in the pathway

Cancer pathways

0.00002

23

327

Glycolysis/Gluconeogenesis

0.00031

8

66

Phospholipase

0.00227

5

38

Salvage pathways of pyrimidine deoxyribonucleotides

0.00641

2

5

Dolichyl-diphosphooligosaccharide biosynthesis

0.01704

2

8

Uracil degradation II (reductive)

0.01704

2

8

Thymine degradation

0.01704

2

8

Methylthiopropionate biosynthesis

0.02600

1

1

Pentose phosphate pathway

0.02647

2

10

MAPK signaling pathway

0.03237

12

257

N-Glycan biosynthesis

0.03827

4

49

NAD salvage pathway II

0.04358

2

13

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