Table 1 Effect of EtOAc extracts of indicated SDS parts on New Zealand white rabbit platelet aggregation (\(\bar{X}\) mean ± SD, n = 10).

From: Antithrombotic effects and related mechanisms of Salvia deserta Schang root EtOAc extracts

Faction

Groups

Dose/mg·kg

ADP

MAR/%

MAIR/%

Root

Aspirin

10

15.2 ± 6.5

57.4 ± 12.9

Control

 

35.7 ± 5.2Δ

 

STD Low Dose

10

40.8 ± 11.2Δ

0.0 ± 0.0Δ

STD Middle Dose

20

29.8 ± 8.7Δ

16.5 ± 7.9Δ

STD High Dose

40

10.2 ± 2.6*

71.4 ± 4.1Δ

p-value (STD dose)

 

<0.0001

 

p-value (Aspirin + STD dose)

 

<0.0001

<0.0001

Stem

Aspirin

10

13.3 ± 8.1

67.2 ± 11.7

Control

 

40.6 ± 11.53Δ

 

STD Low Dose

10

42.9 ± 17.3Δ

0.0 ± 0.0Δ

STD Middle Dose

20

43.1 ± 9.5Δ

0.0 ± 0.0Δ

STD High Dose

40

35.5 ± 7.4Δ

12.6 ± 5.8Δ

p-value (STD dose)

 

0.4667

 

p-value (Aspirin + STD dose)

 

<0.0001

<0.0001

Leaf

Aspirin

10

8.2 ± 3.6

70.8 ± 5.1

Control

 

28.1 ± 8.1Δ

 

STD Low Dose

10

30.4 ± 10.7Δ

0.0 ± 0.0Δ

STD Middle Dose

20

24.5 ± 7.3Δ

12.8 ± 1.8Δ

STD High Dose

40

22.8 ± 6.3Δ

18.8 ± 2.4Δ

p-value (STD dose)

 

0.1780

 

p-value (Aspirin + STD dose)

 

<0.0001

<0.0001

Flower

Aspirin

10

8.2 ± 3.6

70.8 ± 5.1

Control

 

28.1 ± 8.1Δ

 

STD Low Dose

12.5

35.6 ± 6.6Δ

0.0 ± 0.0Δ

STD Middle Dose

25

27.1 ± 7.6Δ

3.5 ± 1.6Δ

STD High Dose

50

20.8 ± 2.7Δ

25.9 ± 12.3Δ

p-value (STD dose)

 

0.0002

 

p-value (Aspirin + STD dose)

 

<0.0001

<0.0001

  1. *P < 0.05 significant difference compared to control group; ΔP < 0.05 significant difference compared to aspirin group.
  2. MAIR(%) = platelet aggregation rate of the control group% - platelet aggregation rate of test drug treated group% / platelet aggregation rate of the control group%.