Figure 2
From: Regulation of the Intranuclear Distribution of the Cockayne Syndrome Proteins
Contribution of consensus localization signals to CSB intracellular distribution. (A) Schematic of the domain structure of CSB, and N-terminally GFP-tagged CSB deletion fragments used in this study. See Fig. 1A for further description. (B) Localization pattern of CSB deletion mutants in HeLa cells. Shown are representative images of the five N-terminally GFP-tagged CSB mutants. Bar; 10 µm. (C) Quantification of subcellular localization profile of CSB fragments. The percentage of distribution of CSB fragments into nucleolus (green), nucleoplasm (red) or cytoplasm (blue) was analyzed from images (n = 51–77) of (B). Error bars indicate SD.
