Figure 6
From: Regulation of the Intranuclear Distribution of the Cockayne Syndrome Proteins
CSA protein is sensitive to deletion. (A) Schematic of the domain structure of CSA, and twelve C-terminally GFP-tagged CSA fragments (N1-6 and C1-6) used in this study. Regions of interest in CSA are the five WD40 motifs (41–75, 97–128, 184–218, 243–273, 332–362). (B) Localization pattern of CSA fragments. HeLa cells were transfected with the indicated plasmid, and then visualized for GFP distribution. Each panel includes a live cell image, as well as images of GFP, B23 and DAPI. Bar; 10 µm.
