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Figure 3

From: Female adipose tissue-specific Bscl2 knockout mice develop only moderate metabolic dysfunction when housed at thermoneutrality and fed a high-fat diet

Figure 3

Female Ad-B2(−/−) mice housed at thermoneutrality are not glucose intolerant. (A) Body weight progression of B2(fl/fl), Ad-B2(+/−) and Ad-B2(−/−) mice place at thermoneutrality (30 °C) at eleven weeks of age (n = 5–6). Fat mass (B) and lean mass (C) levels assessed by DEXA normalised to body weight in B2(fl/fl), Ad-B2(+/−) and Ad-B2(−/−) mice after eight weeks at thermoneutrality (n = 5–6). Five hour fasted blood glucose levels (D) and glucose tolerance test (E) in B2(fl/fl), Ad-B2(+/−) and Ad-B2(−/−) mice after nine weeks at thermoneutrality (n = 5–6). All data are presented as the mean ± SEM, *p < 0.05 vs B2(fl/fl), #p < 0.05 vs Ad-B2(+/−).

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