Figure 5

Effect of solasonine, solasodine and solamargine on the cell cycle distribution of HepG2 cells. Cells were exposed to test compounds ( 10 µM) for 24 h (A–D) or 48 h (E–H) and cell cycle histograms were compared to control cells (A,E); and different cell cycle phases were plotted as percent of total events (B,F). Percentages of cells in pre-G1 phase (C,G) and supra-G2 phase (D,H) were assessed numerically and compared to control treatment. Data are presented as mean ± SD (n = 3); and (*)indicates significantly different from control group at P < 0.05.