Table 2 Parameters, associated symbols, and their values employed for CHO cell model.

Extracellular osmolarity

Π _e

300 mM

measured

Intracellular ATP concentration

[ATP]_i

5 × 10⁻⁶ mol/cm³

^{16, 35}

Intracellular ADP concentration

[ADP]_i

6 × 10⁻⁸ mol/cm³

^{16, 35}

Intracellular inorganic phosphate

[P_i]_i

4.9 × 10⁻⁶ mol/cm³

^{16, 35}

Ratio of permeabilities

P_Na: P_K: P_Cl

1:1:5.7

Calc.³⁶

Membrane Na⁺ permeability

P _Na

5.6 × 10⁻⁸ cm/s

Calc.

Membrane K⁺ permeability

P _K

5.6 × 10⁻⁸ cm/s

Exp.

Membrane Cl⁻ permeability

P _Cl

3.2 × 10⁻⁷ cm/s

Calc.

Membrane osmotic water permeability

P _w

0.0012 cm/s

⁵⁵

Partial molar volume of water

V _w

18 cm³/mol

¹⁶

Na⁺/K⁺- ATPase pump density

N

2.56 × 10⁻¹¹ mol/cm²

Exp.

Mean organic osmolyte valence

z _X

−1.2

Calc.

Cell surface area

A

5.3 × 10⁻⁶ cm²

Exp.

Intracellular amount of X⁻

n _X

7.5 × 10⁻¹⁴ mol

Calc.