Figure 5 | Scientific Reports

Figure 5

From: Analysis of expression of the PD-1/PD-L1 immune checkpoint system and its prognostic impact in gastroenteropancreatic neuroendocrine tumors

Figure 5

Simultaneous analysis of peripheral blood and tumor samples. Dot plots of CD3+PD-1+ cells from (a) peripheral blood and (b) tumor specimen from a representative GEP-NET patient. (c) Paired analysis of expression of CD3 + PD-1+ cells in PBMCs and TILs from 3 patients with GEP-NETs. Values represent percentage of CD3 + PD-1+ cells in PBMCs and TILs. P-value from paired T test is shown. (d) Correlation map for the expression of immune markers in TMAs (IHC) and PBMCs (flow cytometry). Values represent the Spearman’s rank correlation coefficient, rho (ρ). Significant negative correlations are shown in orange and significant positive correlations in blue. Color intensity increases with the magnitude of correlation. White color indicates a non-significant correlation.

Back to article page