Figure 2 | Scientific Reports

Figure 2

From: The impact of cigarette smoke exposure, COPD, or asthma status on ABC transporter gene expression in human airway epithelial cells

Figure 2

Cigarette smoking is associated with differential gene expression patterns of select ABC transporters in small airway epithelial cells. Gene expression levels of selected ABC transporters (a, ABCA13; b, ABCB6; c, ABCC1; d, ABCC3) between healthy non-smokers (green) and smokers with no diagnosis of COPD (blue). Significant expression differences are indicated by asterisks (q < 0.05 according to Mann-Whitney U test with Benjamini Hochberg correction). All three datasets used for this analysis (GSE11906, GSE11784, and GSE4498) analyzed epithelial cells from small airways (10th-12th generation) and were generated from the Affymetrix Human Genome U133 Plus 2 microarray platform (using the Mas 5.0 Normalization method). Data distributions are visualized as boxplots (see Methods for additional details).

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