Table 1 Univariate and multivariate analysis of relapse free survival in 104 colorectal cancers.

From: Sox2 is associated with cancer stem-like properties in colorectal cancer

Clinicopathological factors

Univariate

Multivariate

HR

95%CI

P value

HR

95%CI

P value

Gender (male/female)

1.093

0.512ā€“2.382

0.818

Ā Ā Ā 

Location (rectum/colon)

1.694

0.792ā€“3.652

0.172

Ā Ā Ā 

Lymph node dissection (<12/ā‰„12)

0.577

0.137ā€“1.652

0.336

Ā Ā Ā 

Depth (T4/others)

4.383

1.938ā€“11.181

0.0003*

3.466

1.467ā€“9.192

0.004*

Lymph node metastasis (positive/negative)

3.774

1.669ā€“9.629

0.001*

2.125

0.894ā€“5.647

0.090

Histological type (por, sig, muc/tub1, tub2)

2.359

0.379ā€“7.950

0.300

Ā Ā Ā 

Lymphatic duct invasion (positive/negative)

2.384

0.976ā€“7.127

0.057

Ā Ā Ā 

Venus invasion (positive/negative)

2.505

1.108ā€“6.388

0.026*

1.693

0.724ā€“4.432

0.232

Sox2 expression (high/low)

2.453

1.130ā€“5.729

0.023*

2.529

1.148ā€“5.973

0.021*

  1. Abbreviations: por, poorly differentiated adenocarcinoma; sig, signet ring cell carcinoma; muc, mucinous carcinoma; tub1, well-differentiated adenocarcinoma; tub2, moderately differentiated adenocarcinoma;T4, tumor directly invades other organs or structures and/or perforates visceral peritoneum; *P valueā€‰<ā€‰0.05.
Back to article page