Figure 6 | Scientific Reports

Figure 6

From: The reduced activity of PP-1α under redox stress condition is a consequence of GSH-mediated transient disulfide formation

Figure 6

The formation of Cys140, Cys202 and Cys245-centered disulfide networks in PP-1α upon oxidative stress is proposed. (A) Cys140/Cys245/Cys202-centered cysteine-networks (up to 14 Å) being S-glutathionylation targets. (B) Connection of S-glutathionylation and formation of transient disulfides in rPP-1α (red arrows). (C) Summary of distances (in Å) of identified disulfides.

Back to article page