Figure 3
From: Age-Dependent Protection of Insulin Secretion in Diet Induced Obese Mice

Weight gain correlates with energy expenditure in aged mice fed Western diet, but is not dependent on food consumption or spontaneous activity. (a–d) Average weight (a), food consumption (b), spontaneous activity (c), and average energy expenditure (d) in singly-housed aged mice following administration of chow or Western diet (chow, solid, n = 9; WD, cross-hatch, n = 9). (e–g) Weight gain was compared to food consumption (e), spontaneous activity (f), and energy expenditure (g) to acquire correlations. Data are ± SEM and were compared by paired two way ANOVA with Sidak posttest (a–d) and linear regression (e–g). *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001.