Figure 5
From: Age-Dependent Protection of Insulin Secretion in Diet Induced Obese Mice

β-cell mass is increased by Western diet in both young and aged mice. Representative insulin staining and quantification of β-cell mass (a) and α:β-cell ratio (b) in chow and WD-fed young and aged mice as indicated. β-cell mass, n = 9 mice per group, scale bar = 400 μm; α:β-cell ratio, n = 3–4 mice per group, scale bar = 50 μm. Data are ± SEM and were compared by t-test. *P < 0.05.